Parkinson's Disease is the second most common neurological disorder after Alzheimers. It is estimated to affect one million people in just the United States, and $14 billion is spent annually treating it. Also , ten million people are estimated to suffer from Parkinson's Worldwide. Parkinson's is a chronic and progressive disease that persists and worsens over time.
The APOE-e4 gene variant is one of three forms of the APOE gene, with the others being APOE-e2 and APOE-e3. It constitutes a significant genetic risk factor for the development of Alzheimer's disease. Research on APOE-e4 has shown that individuals inheriting one copy of this variant from a parent face a notably higher risk of Alzheimer's compared to those without it.
Epilepsy is a chronic noncommunicable brain condition that affects approximately 50 million people worldwide. Its main symptom is recurrent seizures, which can be brief bursts of involuntary movement impacting a specific part of the body (partial) or the entire body (generalized). Seizure episodes occur due to excessive electrical discharges in clusters of brain cells. These discharges can originate from various brain areas.
Parkinson's disease is a progressive disorder of the nervous system that affects various regions of the brain, notably the substantia nigra, a region responsible for controlling balance and movement. The development of this disease is a result of a complex interplay of environmental and genetic factors, possibly involving multiple components that contribute to its onset.